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A potent and selective inhibitor of cysteine protease cathepsin K (IC50 0.2 nM), discriminating against cathepsin B (1034 nM), L (2995 nM), and S (60 nM). The product Odanacatib has been in clinical evaluation as the first-in-class drug treating postmenopausal women with osteoporosis.
Catalog NO: CT-CG001
Synonym: MK-0822
CAS NO: 603139-19-1
Mol. Formula: C25H27F4N3O3S ∙ 0.1H2O
MW: 527.4
** A snow-white powder, recrystallized, clean (>99.8% by achiral HPLC), optically pure (100%by chiral HPLC), plus a perfect high-precision quantitative elemental analysis. Ship within 1 day.