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Skip Navigation LinksHome > Kinase Inhibitors > JAK1/JAK2 Selective > INCB018424 (Ruxolitinib)
INCB018424 (Ruxolitinib)
INCB018424 (Ruxolitinib) is a potent, selective and orally bioavailable inhibitor of JAK1 (Ki 2.7 nM) and JAK2 (Ki 4.5 nM). Inhibit JAK3 at Ki 343 nM. Over 100 fold selectivity against a broad panel of other kinases.
Catalog NO: CT-INCB
Synonym: Ruxolitinib, INCB18424, INCB-18424
CAS NO: 941678-49-5
Mol. Formula: C17H18N6
MW: 306.4
** in vivo Quality Material. >99% by Achiral and Chiral HPLCs. Anhydrous, validated with high-precision quantitative elemental analysis. Bulk stock, prompt.