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GDC-6036
Divarasib (GDC-6036) is an orally available, potent and selective inhibitor of KRAS G12C mutant with an IC50 of <0.01 μM, and an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells.
Catalog NO: CT-G6036
Synonym: Divarasib
CAS NO: 2417987-45-0
Mol. Formula: C29H32ClF4N7O2
MW: 622.1
** in vivo Quality Material. >99% by achiral and chiral HPLCs (attached), with Confirmed Activity (IC 50 = 8 nM*). Hemihydrtae, validated by a spot-on Elemental Analysis. Bulk (Discounted price for 0.5, 1, 2G, …,). Prompt.