Welcome visitor Log In - or - Register
(
0 items /
$0.00
)
View Cart
Check Out
four ways
Quick Search:
EPZ-5676 (Pinometostat)
EPZ-5676 (Pinometostat) is a potent, selective and S-adenosyl methionine (SAM) competitive inhibitor of DOT1L methyltransferase (Ki = 80 pM), displaying 37,000-fold selectivity over all other methyltransferases tested. It inhibits H3K79 methylation and MLL-fusion target gene expression, and potently and selectively kills acute leukemia cell lines bearing MLL translocations. It is currently in clinical trials.
Catalog NO: CT-EPZ676
Synonym: Pinometostat, EPZ5676
CAS NO: 1380288-87-8
Mol. Formula: C30H42N8O3• 0.5HCl
MW: 580.9
** A white recrystallized crystalline powder (see attached picture), >99% chem and optical purity, + clean 1H-NMR, + a high-precision quantitative elemental analysis. Bulk stock. Ship within 1 day.