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Skip Navigation LinksHome > Kinase Inhibitors > MEK/MAPK > AZD6244 (Selumetinib)
AZD6244 (Selumetinib)
AZD6244 (Selumetinib) is a potent, selective and orally available small molecule inhibitor of MEK1/2 with an enzymatic IC50 value of 14 nM against MEK1. Block ERK1/2 phosphorylation with an IC50 value of 10 nM. Display broad antitumor activities in cell lines and in animal models either as a single agent, or in combination with other antitumor agents.
Catalog NO: CT-A6244
Synonym: ARRY-142886, Selumetinib
CAS NO: 606143-52-6
Mol. Formula: C17H15BrClFN4O3 ∙ 0.3H2O
MW: 463.1
** in vivo Quality Material. A clean product with 99.5% chemical purity. Bulk stock. Prompt.