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Home > Hippo Pathway Signaling Inhibitor > NVP-IAG933

NVP-IAG933

NVP-IAG933 (IAG933) is a selective and orally efficacious YAP1/WWTR1(TAZ)-pan TEAD protein-protein interaction inhibitor, the first class of small molecules potently disrupting the YAP-TEAD interaction by direct competition (ref. 1).

Catalog NO:	CT-IAG933
Synonym:	IAG933
CAS NO:	2714434-21-4
Mol. Formula:	C27H26ClF2N3O4
MW:	530.0

** * in vivo Quality Material. >99.5% Pure by Achiral and Chiral HPLCs (attached). Bulk stock (Discounted price for 0.2, 0.5, 1G, 2G, …). Same Day Shipping.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	5 mg	$200.00	YES
2	10 mg	$300.00	YES
3	50 mg	$900.00	YES
4	100 mg	$1,500.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99% by Achiral and Chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

IAG-933 (IAG933), Lot 01, Certificate of Analysis .pdf
IAG-933, Lot 01, Visual Appearance.pdf
C_K, IAG-933, Lot 01, Achiral HPLC.pdf
C_K, IAG-933, Lot 01, Chiral HPLC.pdf
C_K, IAG-933, Lot 01, LC-MS.pdf

1. Chapeau, E.A., Sansregret, L., Galli, G.G. et al. Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers. Nat Cancer (2024). https://doi.org/10.1038/s43018-024-00754-9

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