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Factor VIIa inhibitor

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PKMYT1 Kinase Inhibitor

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Monocarboxylate Transporter 1 (MCT 1) Inhibitor

Mutant Isocitrate Dehydrogenase-1 (IDH1) Inhibitor

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CBP/P300 Bromodomain Inhibitor

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DNMT1 (DNA Methyltransferase 1) inhibitor

DOT1L Methyltransferase Inhibitor

EP300/CBP HAT (Histone Acetyltransferases) Inhibitor

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EZH2 (Mutant) METHYLTRANSFERASE INHIBITOR

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Angiotensin II receptor (AT1)

Endothelin receptor antagonist (type A specific)

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HMG-CoA reductase inhibitor

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IMPDH Inhibitor

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Liver X receptor (LXR) Agonist/Modulator

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Toll-like Receptor Agonist

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Anti-angiogenesis

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Arginase Inhibitor

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Prostanoid ligand

RIP1 (RECEPTOR INTERACTING PROTEIN 1) KINASE

TGFβ Kinase Inhibitor

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Adenosine 2A Receptor Antagonist

Arginase Inhibitor

CD73 (ecto-5'-nucleotidase) Inhibitor

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IDO1 (Indoleamine 2,3-dioxygenase 1) Inhibitor

IKZF1/3 (Zinc Finger Protein 1/3)

Immunoproteasome Inhibitor

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SHP2 Phosphatase Inhibitor

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SUMOylation Inhibitor

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Topoisomerase I

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Kinesin (CENP-E) Inhibitor

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KRAS-PDEδ Interaction Inhibitor

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Arginase Inhibitor

Glutaminase Inhibitor

IDH (Isocitrate Dehydrogenase) Inhibitors

IMPDH (Inosine Monosphosphate Dehydrogenase) Inhibitor

MAT2A Inhibitor

Monocarboxylate Transporter 1 (MCT 1) Inhibitor

Monocarboxylate Transporter 4 (MCT 4)

OXPHOS (Mitochondrial Oxidative Phosphorylation of Complex I) Modulator

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Monocarboxylate Transporter 1 (MCT 1) Inhibitor

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Neuroactive/BBB Penetrant

Orexin Receptor Antagonists

SDAM (Serotonin-Dopamine Activity Modulator)

TRK (Tropomyosin Receptor Kinase)(Tyrosine Receptor Kinase) Inhibitor

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CRM1 (exportin 1) Inhibitor(s)

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HCV Protease Inhibitor

HIV-1 integrase Inhibitor

Oxidoreductase Inhibitor

P-p68 (Phosphorylated-p68 RNA Helicase) Inhibitor

Thymidylate synthase inhibitor

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p53–MDM2 Interaction Inhibitor

p53 Reactivator

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PTPN2/N1 (Protein Tyrosine Phosphatase Non-Receptor Type 2/1) Inhibitors

SHP2 Phosphatase Inhibitor

Wip1 Phosphatase Inhibitor

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PARP (Poly (ADP-ribose) polymerase)

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Stem cell research

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NADD8-Activating Enzyme Inhibtor

Proteasome Inhibitor

SUMOylation Inhibitor

Ubiquitin-Activating Enzyme Inhibitor

USP1 (Ubiquitin Specific Protease 1)

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Home > Epigenetics Resch Products > EP300/CBP HAT (Histone Acetyltransferases) Inhibitor > DS-9300

DS-9300

DS-9300 is an orally active, highly potent and selective EP300/CBP HATs (Histone Acetyltransferases) inhibitor with an IC₅₀ value of 28 nM (ref. 1).

Catalog NO:	CT-DS9300
Synonym:
CAS NO:	2259641-46-6
Mol. Formula:	C25H26F3N5O3
MW:	501.5

** in vivo Quality material. >99% Pure by Achiral and Chiral HPLCs (Attached). Validated Absolute Configuration. Anhydrous, validated by a spot-on Elemental Analysis. Bulk stock (Discounted price for 0.5, 1, 2G, …,). Same day shipping.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	5 mg	$180.00	YES
2	10 mg	$250.00	YES
3	50 mg	$750.00	YES
4	100 mg	$1,250.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99% by Achiral and Chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

DS-9300, Lot 01, Certificate of Analysis,.pdf
DS-9300, Lot 01, Visual Appearance.pdf
C_K, DS-9300, Lot 01, Chiral HPLC.pdf
C_K, DS-9300, Lot 01, HPLC-MS.pdf

1. Ryutaro Kanada, et al. Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor, J. Med. Chem. 2023, 66, 1, 695–715

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