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Y-27632 Dihydrochloride
Y-27632 dihydrochloride is a potent and ATP-competitive ROCK (Rho-kinase) inhibitor. It inhibits ROCK1 (p160 ROCK), ROCK2, PKA, PKC and MLCK with Ki values of 0.14-0.22, 0.3, 25, 26 and > 250 μM, respectively. It is Cell-permeable, orally bioavailable and in vivo active.
Catalog NO: CT-Y27632
Synonym:
CAS NO: 129830-38-2
Mol. Formula: C14H21N3O • 2HCl
MW: 320.3 (or refer to the Certificate of Analysis, batch-specific)
** in vivo Quality Material. >99% Pure by Achiral and Chiral HPLCs (attached). Dihydrochloride, validated by a spot-on Elemental Analysis. Bulk stock (Discounted price for 0.5, 1G, …). Same Day Shipping.