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Factor VIIa inhibitor

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PARG (Poly (ADP-ribose) Glycohydrolase) Inhibitor.

PCNA (Proliferating Cell Nuclear Antigen)

PRC2 (the catalytic subunit of polycomb repressive complex 2) >

PKMYT1 Kinase Inhibitor

SMAC Mimics and Inhibitors of IAP

TTK (Human Protein Kinase Monopolar Spindle 1 (hMps1))

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Monocarboxylate Transporter 1 (MCT 1) Inhibitor

Mutant Isocitrate Dehydrogenase-1 (IDH1) Inhibitor

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DNMT1 (DNA Methyltransferase 1) inhibitor

DOT1L Methyltransferase Inhibitor

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EZH2 (Mutant) METHYLTRANSFERASE INHIBITOR

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Lysine specific demethylase 1 (LSD1) Inhibitor

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PRC2 (the catalytic subunit of polycomb repressive complex 2)

PRMT5 (Protein Arginine Methyltransferase 5) Inhibitors/Modulators

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Adenosine Receptor Ligands

Angiotensin II receptor (AT1)

Endothelin receptor antagonist (type A specific)

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HMG-CoA reductase inhibitor

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Mutant-IDH1 Inhibitor

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IMPDH Inhibitor

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Liver X receptor (LXR) Agonist/Modulator

RORγ (Retinoic Acid-related Orphan Receptor gamma (γ )) Agonist

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Toll-like Receptor Agonist

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Anti-angiogenesis

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Arginase Inhibitor

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Prostanoid ligand

RIP1 (RECEPTOR INTERACTING PROTEIN 1) KINASE

TGFβ Kinase Inhibitor

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Adenosine 2A Receptor Antagonist

Arginase Inhibitor

CD73 (ecto-5'-nucleotidase) Inhibitor

CBP/β-catenin Modulators

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RORγ (Retinoic Acid-related Orphan Receptor gamma (γ )) Agonist

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SUMOylation Inhibitor

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Topoisomerase I

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Kinesin (CENP-E) Inhibitor

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G12C Mutant Inhibitors

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KRAS-PDEδ Interaction Inhibitor

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Tri-complex KRAS G12C (ON) Inhibitor

Tri-complex KRAS-G12CV (ON) Inhibitor

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Arginase Inhibitor

Glutaminase Inhibitor

IDH (Isocitrate Dehydrogenase) Inhibitors

IMPDH (Inosine Monosphosphate Dehydrogenase) Inhibitor

MAT2A Inhibitor

Monocarboxylate Transporter 1 (MCT 1) Inhibitor

Monocarboxylate Transporter 4 (MCT 4)

OXPHOS (Mitochondrial Oxidative Phosphorylation of Complex I) Modulator

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Monocarboxylate Transporter 1 (MCT 1) Inhibitor

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Activator of NAMPT (Nicotinamide PphosphoribosylTransferase)

Neuroactive/BBB Penetrant

Orexin Receptor Antagonists

SDAM (Serotonin-Dopamine Activity Modulator)

TRK (Tropomyosin Receptor Kinase)(Tyrosine Receptor Kinase) Inhibitor

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HCV Protease Inhibitor

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Thymidylate synthase inhibitor

WRN Helicase Inhibitor

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p53–MDM2 Interaction Inhibitor

p53 Reactivator

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PTPN2/N1 (Protein Tyrosine Phosphatase Non-Receptor Type 2/1) Inhibitors

SHP2 Phosphatase Inhibitor

Wip1 Phosphatase Inhibitor

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PARP (Poly (ADP-ribose) polymerase)

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Dipeptidyl Peptidase I (DPP1) (Cathepsin C)

Glycoside Hydrolase

Neprilysin (MME)

PDE4 ( phosphodiesterase type 4)

PLA2 Inhibitors

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Stem cell research

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NADD8-Activating Enzyme Inhibtor

Proteasome Inhibitor

SUMOylation Inhibitor

Ubiquitin-Activating Enzyme Inhibitor

USP1 (Ubiquitin Specific Protease 1)

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Home > Kinase Inhibitors > EGFR Mutants > WZ4002

WZ4002

A potent and selective EGFR kinase inhibitor against mutant EGFR T790M. A potential agent for treatment of some drug-resistant non-small cell lung cancers.

Catalog NO:	CT-WZ4002
Synonym:
CAS NO:	1213269-23-8
Mol. Formula:	C₂₅H₂₇ClN₆O₃
MW:	494.97

** in vivo Quality material. >99% Pure by HPLC. Anhydrous, validated with a spot-on Quantitative Elemental Analysis. Bulk stock (discounted price for 1G, 2G, …,). Same day shipping.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	10 mg	$120.00	YES
2	50 mg	$320.00	YES
3	100 mg	$500.00	YES
4	200 mg	$800.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99% (HPLC)

Original QC Data : LC/MS, ¹HNMR

Please Pick Batch NO:

WZ4002, lot 01, Certificate of Analysis.pdf
WZ4002, Lot 01, Appearance (color).pdf

1. W. Zhou, et al., Novel mutant-selective EGFR kinase inhibitors against EGFR T790M, Nature (2009) 462, 1070-1074.

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