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Home > Kinase Inhibitors > mTOR > TORIN 2

TORIN 2

TORIN 2 is an orally available, potent and selective ATP-competitive inhibitor of mTOR (Mammalian Target of Rapamycin) kinase with an IC50 of 0.25 nM, a 800 fold selectivity over PI3K (IC50 = 200 nM) (ref. 1).

Catalog NO:	CT-TORIN2
Synonym:	TORIN2
CAS NO:	1223001-51-1
Mol. Formula:	C24H15F3N4O
MW:	432.4

** 99.9% pure. in vivo Quality material. Anhydrous, validated by spot-on microanalysis. Bulk Stock (get discounted quote for larger qty). Same day shipping.

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NO	Size	Price	In Stock	Quantity
1	10 mg	$80.00	YES
2	50 mg	$240.00	YES
3	100 mg	$390.00	YES
4	200 mg	$690.00	YES

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Solubility : refer to Certificate of Analysis

Storage : refer to Certificate of Analysis

Purity : 99.9% by HPLC at 214 and 254 nm

Original QC Data : HPLC-MS, 1H-NMR, and Quantitative Elemental Analysis Report

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TORIN 2, Lot 01, Certificate of Analysis.pdf
TORIN 2, Lot 01, Visual Appearance.pdf

1. Liu, Q., et al, Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2( 1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer. J Med Chem. 2011, 54, 1473-1480

2. Liu Q., et al. "Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR." Cancer Res. 73: 2574-2586 (2013).

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