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TAK-931 (Simurosertib)
TAK-931 (Simurosertib) (optically pure) is an orally bioavailable, ATP competitive, potent and selective inhibitor of CDC7 (cell division cycle 7-related protein kinase) with IC50 < 0.3 nM, and highly selective on target when compared with other 308 kinases. It demonstrates strong antitumor activities in both in vitro and in vivo models, and is currently in clinical evaluations.
Catalog NO: CT-TAK931
Synonym: TAK931
CAS NO: 1330782-76-7
Mol. Formula: C17H19N5OS
MW: 341.4
** in vivo Grade Material. 99.7-100% by achiral and chiral HPLCs. A milk-white crystalline powder (picture attached), monohydrate, validated by a spot-on quantitative microanalysis. Bulk stock (Multi grams)! Prompt.