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Home > Toll-like Receptor Modulators > TAK-242 (Resatorvid)

TAK-242 (Resatorvid)

Resatorvid (TAK-242) is a selective and cell permeable toll-like receptor 4 (TLR4) signaling inhibitor. It Binds to intracellular domain of TLR4 and Inhibits LPS-induced cytokine production in vitro (IC50 values are 1.3, 1.3 and 3.2 nM for IL-6, TNFα and NO production, respectively). Reduces lesion volume in a mouse model of cerebral cavernous malformations (CCMs). Also attenuates increased cytokine levels in a mouse sepsis model, when given in combination with ceftazidime.

Catalog NO:	CT-TAK242
Synonym:	Resatorvid
CAS NO:	243984-11-4
Mol. Formula:	C15H17ClFNO4S
MW:	361.8

** in vivo Quality Material. >99.5% by Achiral and Chiral HPLCs (Attached). Anhydrous, validated with a spot-on quantitative elemental analysis. Bulk stock (Discounted price for 0.5G, 1G, ..). Same day shipping.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	10 mg	$120.00	YES
2	50 mg	$360.00	YES
3	100 mg	$560.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : 99% by Achiral and Chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

TAK-242 Lot 01 Certificate of Analysis.pdf
TAK-242 Lot 01 Visual Appearance.pdf
C_K, TAK-242, Lot 01, Achiral HPLC.pdf
C_K, TAK-242, Lot 01, Chiral HPLC.pdf
C_K, TAK-242, Lot 01, NMR.pdf

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