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Home > Isomerase Inhibitor/Modulator > Topoisomerase I > SN-38

SN-38

SN38 is an inhibitor of topoisomerase I

Catalog NO:	CT-SN38
Synonym:
CAS NO:	86639-52-3
Mol. Formula:	C₂₂H₂₀N₂O₅
MW:	392.31

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	25 mg	$60.00	YES
2	100 mg	$150.00	YES
3	500 mg	$450.00	YES

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Solubility : Soluble in DMSO to 100 mM

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% (HPLC)

Original QC Data : ¹HNMR, HPLC

Please Pick Batch NO:

SN-38, Current Lot, Certificate of Analysis

1. Cao Y, Jin ZX, Tong XP, et al., Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis., Anticancer Res. 2010 Oct;30(10):3911-7.

2. Pastorino F, Loi M, Sapra P, et al., Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor. Clin Cancer Res. 2010 Oct 1;16(19):4809-21.

3. Wang W, Ghandi A, Liebes L. et al., Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivo., J Neurosurg. 2010 Apr 23. [Epub ahead of print].

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