Welcome visitor Log In - or - Register
0 items /
View Cart
Check Out
four ways
Quick Search:
Skip Navigation LinksHome > Kinase Inhibitors > PI3K - p110 Alpha (α) Specific > Serabelisib (MLN1117, INK1117, TAK-117)
Serabelisib (MLN1117, INK1117, TAK-117)
Serabelisib (MLN1117, TAK-117, INK1117) is an orally bioavailable, PI3K p110α- isoform specific inhibitor with an in vitro IC50 of 15 nM, highly selective against other isoforms (p110β, p110γ and p110δ) and mTOR (no significant inhibitions at 1 μM concentration). It displayed significant efficacy in several PI3Kα mutant-specific preclinical mouse xenograft tumor models, and blocked signaling to Akt and inhibited growth of cancer cells harboring wild-type or mutated p110α. It is currently under clinical evaluation.
Catalog NO: CT-SERA
Synonym: MLN1117, INK1117, TAK-117
CAS NO: 1268454-23-4
Mol. Formula: C19H17N5O3
MW: 363.4 (refer to Certificate of Analysis, batch-specific)
** A milk-white powder (picture attached), >99% Purity + impeccable 1H-NMR, + a perfect quantitative elemental analysis. Bulk stock!!. Same day shipping.