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SCH900776 (MK-8776)
SCH900776 (MK-8776) is a potent, selective and orally bioavailable inhibitor of CHK1(IC50 = 3 nM), highly selective against CHK2 (IC50 = 1500 nM) and CDK2 (IC50 = 160 nM).* It is currently in clinical trials.
Catalog NO: CT-SCH900
Synonym: MK-8776
CAS NO: 891494-63-6
Mol. Formula: C15H18BrN7∙1.8HCl∙0.4H2O
MW: 449.1
** A pale yellow solid (see attached picture), single isomer (R-enantiomer - clinically active isomer), 99% ee by Chiral HPLC,* + impeccable 1H-NMR, coming with a high-precision Quantitative Elemental Analysis. Ship within 1 day.