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Ramatroban
Ramatroban (BAY-u3405) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of the thromboxane receptor (TP receptor). BAY-u3405 is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM.  BAY-u3405 is more potent at the DP2 receptor than the TP receptor by 4-5 fold. BAY-u3405 is therefore a useful tool for the elucidation of PGD2/DP2 function in eosinophils, basophils, and other cells of the TH2 cell-type.
Catalog NO: CT-RAM
Synonym: Bay u3405
CAS NO: 116649-85-5
Mol. Formula: C21H21FN2O4S
MW: 416.5
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