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PF-06855800 (PF06855800)
PF-06855800 (PF06855800) is a clinical-stage, SAM-pocket-binding (SAM competitive) PRMT5 inhibitor with high selectivity and affinity (PRMT5-MEP-50, Ki < 0.1 nM) and demonstrates robust and efficacious antiproliferative activity in both in vitro and in vivo models.
Catalog NO: CT-PF0685
Synonym: PF06855800
CAS NO: 1989620-04-3
Mol. Formula: C17H16ClFN4O4∙H2O
MW: 412.8 (or refer to the Certificate of Analysis, batch-specific)
** in vivo Quality material, >99% pure by Achiral and Chiral HPLCs (attached). Monohydrate, validated by a spot-on a Quantitative Elemental Analysis. Bulk stock. Same day shipping.