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Skip Navigation LinksHome > Kinase Inhibitors > PI3K/mTOR > PF-04691502
PF-04691502 is a potent, selective and orally active ATP-competitive PI3K/mTOR inhibitor with Ki values of 1.6, 1.8, 1.9, 2.1 and 16 nM for human PI3K δ, α, γ, β, and mTOR, respectively, displaying no significant inhibitory activity towards more than 80 protein kinases (concentration ≥ 10 μM) including hVps34, PI3K downstream kinases, and MAPK family members, and inducing robust cell cycle arrest at the G1 phase in U87MG cancer cells and antitumor activity in SKOV3 ovarian cancer xenograft models.
Catalog NO: CT-PF1502
CAS NO: 1013101-36-4
Mol. Formula: C22H27N5O4
MW: 425.5
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