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Home > Kinase Inhibitors > P21-Activated Kinases > PF-03758309

PF-03758309

PF-03758309 is a potent, orally bioavailable and ATP-competitive inhibitor of p21-activated kinase (PAK), a downstream effector of the Rho family functioning as a signaling node for various oncogenic pathways.

Catalog NO:	CT-PF0375
Synonym:	PF-3758309
CAS NO:	898044-15-0 (free base), 1279034-84-2 (HCl)
Mol. Formula:	C₂₅H₃₀N₈OS ∙ 2HCl
MW:	563.5 (or refer to certificate of analysis, batch-specific)

** in vivo Quality Material. >99% pure by Achiral and Chiral HPLCs (Attached). Dihydrochloride salt, verified by Elemental Analysis. Bulk stock (discounted price for 0.5G, 1G, 2G, …). Same day shipping.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	5 mg	$85.00	YES
2	10 mg	$125.00	YES
3	50 mg	$350.00	YES
4	100 mg	$590.00	YES

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Solubility : Soluble in DMSO, Water

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% chem purity (HPLC), 100% optical purity (Chiral HPLC)

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC and Quantitative Elemental Analysis

Please Pick Batch NO:

PF-03758309, Lot 04, COA.pdf
PF-03758309, Lot 04, Visual Appearance.pdf

1. B. W. Murray, et al., Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth, PNAS U S A, 2010 May 18;107(20):9446-51.

2.

3. Confirmed by a high-precision quantitative elemental analysis.

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