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Skip Navigation LinksHome > Kinase Inhibitors > EGFR Mutants > Olmutinib (BI 1482694, HM71224)
Olmutinib (BI 1482694, HM71224)
Olmutinib (BI 1482694, HM61713) is a third-generation, orally bioavailable and irreversible Tyrosine Kinase Inhibitor, potently and selectively targeting EGFR mutants with Ki values of ~10 nM (in vitro cell assays, against sensitizing (Del19, L858R) and resistance (T790M) EGFR mutations), highly selective over Wt EGFR (Ki = >2000nM, >200-fold selectivity). It is an FDA -designated Breakthrough Therapy for lung cancer.
Catalog NO: CT-HM712
Synonym: BI 1482694, HM71224
CAS NO: 1353550-13-6
Mol. Formula: C26H26N6O2S
MW: 486.6
** A pale yellow crystalline powder (see attached picture), clean (>99.5% by HPC) + impeccable1H-NMR, + a perfect Quantitative Elemental Analysis. Bulk stock. Ship within 1 day.