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NVP-BKM120 (Buparlisib)
NVP-BKM120 (Buparlisib) is an orally bioavailable and selective pan-class I phosphatidylinositol-3 kinase (PI3K) inhibitor with in vitro IC50 values of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ isoforms, respectively. It is much less effective on inhibiting the class III PI3K Vps34 and mTOR, and has no effect on PI4Kβ. It is currently in clinical trials for cancer treatment.
Catalog NO: CT-BKM120
Synonym: Buparlisib, BKM120
CAS NO: 944396-07-0
Mol. Formula: C18H21F3N6O2
MW: 410.4 (refer to Certificate, batch-specific)
** in vivo grade material. 99.9% Purity by HPLC. A snow-white crystalline powder (pic attached), clean and impeccable with a spot-on quantitative microanalysis. Bulk stock!! Ship within 1 day.