NVP-BGJ398 (Infigratinib) - Chemietek

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Home > Kinase Inhibitors > FGFR (Fibroblast Growth Factor Receptor) > NVP-BGJ398 (Infigratinib)

NVP-BGJ398 (Infigratinib)

NVP-BGJ398 is a potent, selective and orally active pan-FGFR inhibitor, with IC50s of 0.9, 1.4, 1.0 and 60 nM for FGFR1, 2, 3 and 4, respectively.

Catalog NO:	CT-BGJ398
Synonym:	Infigratinib, BGJ398
CAS NO:	872511-34-7
Mol. Formula:	C₂₆H₃₁Cl₂N₇O₃
MW:	560.5 (or refer to the Certificate of Analysis, batch-specific)

** in vivo Quality Material. >99% Pure by HPLC (attached), a white recrystallized powder. Hemihydrate, validated with a spot-on Quantitative Elemental Analysis. Bulk Stock!! Prompt

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	10 mg	$95.00	YES
2	50 mg	$180.00	YES
3	100 mg	$300.00	YES
4	200 mg	$500.00	YES
5	500 mg	$950.00	YES

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Solubility : In DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99% by HPLC

Original QC Data : HPLC, ¹H-NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

NVP-BGJ398, Lot 05, Certificate of Analysis.pdf

Vito Guagnano, et al, Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase, J. Med. Chem., 2011, 54 (20), pp 7066–7083

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