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MRTX849 (Adagrasib) is an orally available, potent, mutation-selective, and irreversible covalent inhibitor of KRAS-G12C, currently under evaluation as antitumor therapies by modulating KRAS-dependent signal transduction as a single agent, or in combination of with SHP2 inhibitor TNO155 (our Prod No CT-TNO155).
Catalog NO: CT-MRTX849
Synonym: Adagrasib, MRTX-849
CAS NO: 2326521-71-3
Mol. Formula: C32H35ClFN7O2
MW: 604.1
** in vivo Quality Material. >99.5% by achiral and chiral HPLCs (attached ). Validated Activity* and Chirality**. Hemihydrate, confirmed with a spot-on Quantitative Elemental Analysis. Clean and impeccable. Bulk Stock!! Prompt