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MK-5108 (VX-689) is a potent, selective and ATP competitive inhibitor of Aurora A with IC50 < 1 nM, highly selective (220- and 190-fold) against Aurora B and C, respectively. It is currently in clinical evaluations.
Catalog NO: CT-MK5108
Synonym: VX-689
CAS NO: 1010085-13-8
Mol. Formula: C22H21ClFN3O3S ∙ 1.9HCl
MW: 531.2
** 99.5% purity (HPLC at 214, 254 and 280 nm), coming as a HCl salt (1.9 eq.), manifested by a Quantitative Elemental Analysis. Grams in stock from Indianapolis USA. Ship within 1 day.