LOXO-101 (Larotrectinib) - Chemietek

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Home > Kinase Inhibitors > TRK (Tropomyosin Receptor Kinase) (Tyrosine Receptor Kinase) > LOXO-101 (Larotrectinib)

LOXO-101 (Larotrectinib)

LOXO-101 (Larotrectinib) is an oral, potent and selective ATP-competitive pan-TRK inhibitor, with sub-nanomolar potency in IC50 values for all three TRK family members (TrkA, TrkB and TrkC), and >100-fold selectivity over other kinases. Displays robust in vitro and in vivo antitumor activities. It is currently in clinical evaluation.

Catalog NO:	CT-LX101
Synonym:	Larotrectinib, ARRY-470
CAS NO:	1223403-58-4
Mol. Formula:	C21H22F2N6O2∙1/2H2O
MW:	437.4

** in vivo grade material. A single isomer (out of possible four), 99.9% chemical and stereomerical purity by achiral and chiral HPLCs (All QC docs attached), hemihydrate (by a spot-on microanalysis). Bulk Stock. Same day shipping.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	10 mg	$70.00	YES
2	50 mg	$140.00	YES
3	100 mg	$220.00	YES
4	200 mg	$380.00	YES

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Solubility : refer to Certificate of Analysis

Storage : refer to Certificate of Analysis

Purity : 99.9% chemical and stereomerical purity by achiral and chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, 1H-NMR, and Elemental Analysis Report

Please Pick Batch NO:

LOXO-101 (Larotrectinib), Lot 01, Certificate of Analysis.pdf
LOXO-101, Lot 01, Visual Appearance.pdf

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