Welcome visitor Log In - or - Register
0 items /
View Cart
Check Out
four ways
Quick Search:
KPT-330 (Selinexor)
KPT-330 is a first-in-class oral selective inhibitor of nuclear export proteins, inhibiting its nuclear export function by covalently binding to Cys528 in the nuclear export signal-binding groove of CRM1 (exportin 1). It demonstrates potent anticancer activity, inducing apoptosis in various leukemia and multiple myeloma cell lines (IC50s = 34-203 nM) and mouse models. It is currently being evaluated in several phase I and phase II clinical trials in both solid and hematological malignancies (refs 1-3).
Catalog NO: CT-KPT330
Synonym: Selinexor
CAS NO: 1393477-72-9
Mol. Formula: C17H11F6N7O
MW: 443.4
** in vivo Quality Material. A recrystallized powder. >98.5% by HPLC. Anhydrous, validated by a spot-on quantitative microanalysis. Bulk stock! Same day shipping.