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JAB-3068 is a potent, selective and orally bioavailable allosteric inhibitor of SHP2 (protein tyrosine phosphatase) (PTP) non-receptor type 11 (SHP2; Src homology region 2 domain phosphatase; PTPN11), with potential antineoplastic activity. It is efficacious as an oral monotherapy as well as an immune-oncology modulator.
Catalog NO: CT-JAB3068
Synonym: JAB3068
CAS NO: 2169223-48-5
Mol. Formula: C22H26F2N6O2S
MW: 476.5
** in vivo Quality Material. >99.5% Pure by achiral and chiral HPLCs, an Enantiomerically pure single isomer (100% by Chiral HPLC). Free base (Salt-free), anhydrous, validated by a spot-on microanalysis, made for in vivo studies. Bulk stock, prompt.