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I-BET726 (GSK1324726A)
I-BET726 (GSK1324726A) is a potent and selective, tetrahydroquinoline-based small molecule ligand binding to BET proteins with IC50s (FRET) of 7.4, 7.1, 7.0, and 7.3 nM for BRD2, BRD3 BRD4 and BRDT, respectively (Ref. 2), showing no binding potency towards other proteins.
Catalog NO: CT-BET726
Synonym: GSK1324726A
CAS NO: 1300031-52-0
Mol. Formula: C25H23ClN2O3
MW: 434.9
** in vivo grade material. Optically Pure Source (ref 3). 99.5-100% by achiral and chiral HPLCs. A recrystallized powder, with spot-on quantitative elemental analysis. Bulk stock! Ship within 1 day.