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GSK778 (iBET-BD1)
GSK778 (iBET-BD1) is a domain-selective and orally active BET inhibitor targeting specifically BDI (Bromodomain I) with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively (ref 1).
Catalog NO: CT-GSK778
Synonym: iBET-BD1
CAS NO: 2451862-42-1
Mol. Formula: C30H33N5O3
MW: 511.6
** >99% by Achiral and Chiral HPLCs. A single Enantiomer (>99% by Chiral HPLC). Hemihydrate, validated by a spot-on Quantitative Elemental Analysis. In stock, same day shipping.