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GSK2334470
GSK2334470 is a highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1) with IC50 of 10 nM. It does not suppress activity on other 96 kinases, including Aurora, ROCK, p38 MAPK and PI3K. GSK2334470 has been used in cells to ablate T-loop phosphorylation and activate SGK, S6K1 and RSK as well as suppress the activation of Akt.
Catalog NO: CT-GSK233
Synonym:
CAS NO: 1227911-45-6
Mol. Formula: C25H34N8O ∙ 0.3H2O
MW: 468
** in vivo grade material. 99.9-100% by achiral and chiral HPLCs. A stereomerically pure single isomer (Clinically active isomer) with 100%ee, de (All QC Docs attached), coming with a quantitative microanalysis. Bulk stock!! Ship within 1 day.