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Home > Immuno/Inflammatory Mediators > Anti-fibrosis > GS-4997 (Selonsertib)

GS-4997 (Selonsertib)

GS-4997 (Selonsertib), a clinical stage, orally bioavailable small molecule, is an inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.

Catalog NO:	CT-G4997
Synonym:	Selonsertib
CAS NO:	1448428-04-3
Mol. Formula:	C24H24FN7O
MW:	445.5 (or refer to Certificate of Analysis, batch-specific)

** in vivo grade material. A snow-white powder (pic attached), 99.5% pure by HPLC, coming with a high-precision quantitative elemental analysis. Bulk stock. Prompt.

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NO	Size	Price	In Stock	Quantity
1	10 mg	$100.00	YES
2	50 mg	$260.00	YES
3	100 mg	$450.00	YES

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Solubility : Refer to Certificate of Anlysis

Storage : Refer to Certificate of Anlysis

Purity : 99.5% by achiral HPLC, Lot 01.

Original QC Data : HPLC-MS, 1H-NMR and Quantitative Elemental Analysis

Please Pick Batch NO:

GS-4997 (Selonsertib), Lot 01, Visual Appearance.pdf
GS-4997 (Selonsertib), Lot 01, Certificate of Analysis.pdf

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