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Etoposide phosphate
Etoposide phosphate is a phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent.
Catalog NO: CT-EPH
Synonym: VP-16
CAS NO: 117091-64-2
Mol. Formula: C29H33O16P
MW: 668.54
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