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Epacadostat (INCB24360, INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, highly selective over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Displays potent in vitro and in vivo immunomodulating and antineoplastic activities. Currently in clinical trials.
Catalog NO: CT-EPAC
Synonym: INCB24360, INCB024360
CAS NO: 1204669-58-8
Mol. Formula: C11H13BrFN7O4S
MW: 438.2
** in vivo Grade Material. A snow-white powder, re-crystallized (see attached picture), >99.5% by HPLC, coming with a spot-on quantitative elemental analysis. Bulk stock. Prompt.