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Home > Immuno-oncology Modulators > IDO1 (Indoleamine 2,3-dioxygenase 1) Inhibitor > Epacadostat

Epacadostat

Epacadostat (INCB24360, INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, highly selective over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Displays potent in vitro and in vivo immunomodulating and antineoplastic activities. Currently in clinical trials.

Catalog NO:	CT-EPAC
Synonym:	INCB24360, INCB024360
CAS NO:	1204669-58-8
Mol. Formula:	C₁₁H₁₃BrFN₇O₄S
MW:	438.2

** in vivo Grade Material. A snow-white powder, re-crystallized (see attached picture), >99.5% by HPLC, coming with a spot-on quantitative elemental analysis. Bulk stock. Prompt.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	10 mg	$90.00	YES
2	50 mg	$250.00	YES
3	100 mg	$350.00	YES
4	200 mg	$600.00	YES

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Solubility : See Solubility Data in COA

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% (HPLC)

Original QC Data : HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis

Please Pick Batch NO:

Epacadostat (INCB24360), Lot 06, Certificate of Analysis.pdf
Epacadostat, Lot 06, Visual Appearance.pdf
CHEMIETEK, Epacadostat (INCB24360), Lot 06, HPLC.pdf
CHEMIETEK, Epacadostat (INCB24360), Lot 06, NMR.pdf

* To date (06/25/2015) all other vendors (no exception) offer this compound (INCB24360, INCB024360) with a wrong structure (with CAS No: 914471-09-3, Mol. Formula: C9H7ClFN5O2, Mol. Wt: 271.6). Buyer beware!!

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