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CUDC-305 (DEBIO-0932)
CUDC-305 (DEBIO-0932) is an orally bioavailable inhibitor of Heat Shock Proteins, displaying high affinity for HSP90α/β (about 100 nM in IC50) and HSP90 complex derived from cancer cells (IC50= 48.8 nM). Exhibits high oral bioavailability (96.0%) and selective retention in tumor (half-life, 20.4 hours) compared with normal tissues. BBB Penetrant.
Catalog NO: CT-CU305
Synonym: DEBIO-0932
CAS NO: 1061318-81-7
Mol. Formula: C22H30N6O2S
MW: 442.58
** An off-white crystalline powder, recrystallized (picture attached), clean (>99.5% by HPLC) + impeccable 1H-NMR, coming with an excellent Quantitative Elemental Analysis. Bulk stock!! Ship within 1 day.