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Skip Navigation LinksHome > New & Featured Products > CTX-712 | Rogocekib
CTX-712 | Rogocekib
Rogocekib (CTX-712) is a first-in-class, orally available, highly potent and selective CLK (CDC2-like-Kinase) Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation. CLK kinase is a key regulator of the RNA splicing, a process often dysregulated in cancers like Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS). CTX-712 demonstrates potent inhibition of proliferation in a variety of human tumor cell lines in vitro and elicited robust antitumor activity in vivo in multiple xenograft models (refs 1, 2).
Catalog NO: CT-CTX712
Synonym: Rogocekib, CTX712
CAS NO: 2144751-78-8
Mol. Formula: C19H17FN8O2
MW: 417.4 (or, refer to Certificate of Analysis, batch-specific)
** in vivo Quality Material. >99% by Achiral and Chiral HPLCs (attached). Hemihydrate, validated by a quantitative Elemental Analysis. Bulk stock (Discounted Price for larger Sizes: 0.5, 1, 2G,…,)!! Same day shipping.
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