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Cerdulatinib is a dual inhibitor of Spleen Tyrosine Kinase (Syk) and Janus Kinases (JAKs) with IC50s = 32, 12, 6, 8, and 0.5 nM for Syk, JAK1, JAK2, JAK3, and TYK2, respectively. It was developed for the treatment of hematological malignancies (Refs 1,and 2).
Catalog NO: CT-CERD
Synonym: PRT2070, PRT062070
CAS NO: 1198300-79-6
Mol. Formula: C20H27N7O3S ·1/5H2O
MW: 449.1
** in vivo Quality Material. >99% Purity by HPLC with a spot-on quantitative elemental analysis. Bulk (Grams). Prompt.