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BAY-1895344 (BAY1895344)
BAY 1895344 is an orally available, potent and selective ATR inhibitor with an in vitro IC 50 of 7nM. It potently inhibits the proliferations of a broad spectrum of human tumor cell lines (cellular media IC50 = 78 nM), and exhibits strong in vivo anti-tumor efficacy in both mono- and combination therapy in a variety of xenograft models. It is currently in clinical evaluation.
Catalog NO: CT-BAY189
Synonym: BAY1895344
CAS NO: 1876467-74-1 (Free Base)
Mol. Formula: C20H21N7O
MW: 375.4
** in vivo Quality Material. 99.9%% by achiral and chiral HPLCs, Free base, validated by a spot-on quantitative elemental analysis. Bulk (Multi Grams). Prompt.