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AZD-7648 is an orally available potent and selective next generation DNA-dependent protein kinase (DNA-PK) inhibitor (Enzymatic and Cellular IC50s = 0.6 nM, 91 nM, respectively ), highly selective against a panel of 397 other kinases, including closely-related Kinases such as ATM, ATR, and PI3Kα, β, δ, γ. Exhibits antitumor efficacy either as a monotherapy or in combination with either cytotoxic chemotherapies or novel Anti-Cancer agents.
Catalog NO: CT-A7648
Synonym: AZD-7648
CAS NO: 2230820-11-6
Mol. Formula: C18H20N8O2
MW: 380.4
** in vivo Quality Material. 99.9% Pure by HPLC, clean and impeccable, coming with a spot-on high-precision Quantitative Microanalysis. Bulk stock! Prompt