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AZD4573 (AZD-4573)
AZ4573 is a potent inhibitor of CDK9 with a biochemical IC50 of <3 nM, highly selective (>10 fold) against all other CDKs and kinases. AZD4573 rapidly induces cell death in hematological tumor models (both in vitro and in vivo) through depletion of Mcl-1 (ref. 1).
Catalog NO: CT-A4573
Synonym:
CAS NO: 2057509-72-3
Mol. Formula: C22H28ClN5O2
MW: 429.9
** in vivo Quality Material. 99.5-99.9% by achiral and chiral HPLCs. Hemihydrate, validated by a spot-on quantitative elemental analysis. Bulk stock. Prompt.