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Home > Kinase Inhibitors > ATM (Ataxia Telangiectasia Mutated Kinase) > AZD-0156 (AZD0156)

AZD-0156 (AZD0156)

ATMK (Ataxia Telangiectasia Mutated Kinase), a serine/threonine protein kinase, is upregulated in a variety of cancer cell types, and activated in response to DNA damage and plays a key role in DNA-strand repair. AZD-0156 (AZD0156) is an orally bioavailable small molecule inhibiting the kinase activity of ATM and ATM-mediated signaling, preventing DNA damage checkpoint activation, disrupting DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells. In addition, AZD0156 also sensitizes tumor cells to chemo- and radiotherapy.

Catalog NO:	CT-A0156
Synonym:	AZD0156
CAS NO:	1821428-35-6
Mol. Formula:	C26H31N5O3
MW:	461.6

** in vivo grade material, 99.9% Pure by HPLC. A recrystallized crystalline solid (pic attached), coming with a High-precision Elemental Analysis, Bulk stock. Ship within 1 day.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	10 mg	$100.00	YES
2	50 mg	$250.00	YES
3	100 mg	$420.00	YES
4	200 mg	$720.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : 99.9% (HPLC at 214 and 254 nm)

Original QC Data : HPLC, 1H-NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

AZD0156, Lot 01, Certificate of Analysis.pdf
AZD0156 , Lot 01, Visual Appearance (Color).pdf

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