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Skip Navigation LinksHome > Kinase Inhibitors > MEK/MAPK > Arry-162 (Binimetinib, MEK162)
Arry-162 (Binimetinib, MEK162)
ARRY-162 is a potent, orally bioavailable and non-ATP competitive inhibitor of MEK1/2 (IC50 = 12 nM ) and cellular pERK (IC50 = 11 nM) , selective against a panel of other 220 kinases (has no activity at 10 uM). It shows ex vivo inhibition of cytokine production such as IL-1, TNF and IL-6. It is currently in clinical trials.
Catalog NO: CT-A162
Synonym: Binimetinib, MEK162
CAS NO: 606143-89-9
Mol. Formula: C17H15BrF2N4O3
MW: 441.23
** in vivo Quality Material, white crystalline powder (See attached Quality Controls), with validated purity (>99.5% by HPLC) + clean NMR + spot-on Quantitative microanalysis. Bulk stock, same day shipping.