Arry-162 (Binimetinib, MEK162) - Chemietek

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Home > Kinase Inhibitors > MEK/MAPK > Arry-162 (Binimetinib, MEK162)

Arry-162 (Binimetinib, MEK162)

ARRY-162 is a potent, orally bioavailable and non-ATP competitive inhibitor of MEK1/2 (IC50 = 12 nM ) and cellular pERK (IC50 = 11 nM) , selective against a panel of other 220 kinases (has no activity at 10 uM). It shows ex vivo inhibition of cytokine production such as IL-1, TNF and IL-6. It is currently in clinical trials.

Catalog NO:	CT-A162
Synonym:	Binimetinib, MEK162
CAS NO:	606143-89-9
Mol. Formula:	C₁₇H₁₅BrF₂N₄O₃
MW:	441.23

** in vivo Quality Material, white crystalline powder (See attached Quality Controls), with validated purity (>99.5% by HPLC) + clean NMR + spot-on Quantitative microanalysis. Bulk stock, same day shipping.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	50 mg	$70.00	YES
2	200 mg	$160.00	YES
3	500 mg	$320.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% (HPLC)

Original QC Data : HPLC-MS, ¹HNMR and Quantitative Elemental Analysis

Please Pick Batch NO:

ARRY-162, Lot 02, Certificate of Analysis.pdf
ARRY-162, Lot 02, Appearance (Color).pdf
CHEMIETEK, ARRY-162, Lot 02, HPLC, Re-test.pdf

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