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Home > Kinase Inhibitors > c-Met > ARQ-197

ARQ-197

ARQ-197 is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity. ARQ 197 binds to the c-Met protein and disrupts c-Met signal transduction pathways, which may induce cell death in tumor cells overexpressing c-Met protein or expressing consitutively activated c-Met protein.

Catalog NO:	CT-ARQ197
Synonym:	Tivantinib
CAS NO:	905854-02-6
Mol. Formula:	C₂₃H₁₉N₃O₂
MW:	369.42

** Please ask for quote for other quantities.

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NO	Size	Price	In Stock	Quantity
1	5 mg	$80.00	YES
2	10 mg	$120.00	YES
3	50 mg	$360.00	YES
4	100 mg	$660.00	YES
5	200 mg	$1,000.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : 99% chem and optical purity (HPLC and Chiral HPLC)

Original QC Data : LC/MS, ¹HNMR and Chiral HPLC

Please Pick Batch NO:

ARQ-197, Lot 001, Certificate of Analysis

1. Bagai Rakesh; Fan Weiwen; Ma Patrick C ARQ-197, an oral small-molecule inhibitor of c-Met for the treatment of solid tumors. IDrugs : the investigational drugs journal (2010), 13(6), 404-14.

2. Tomillero A; Moral M A Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology (2010), 32(1), 47-86.

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