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AN2728 (Crisaborole)
AN2728 (Crisaborole) is a non-steroidal, topically administered, boron-containing, anti-inflammatory compound that inhibits Phosphodiesterase 4 (PDE4), mainly acting on Phosphodiesterase 4B (PDE4), activity and thereby suppresses the release of tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines, proteins believed to be involved in the immune response and inflammation. The boron atom helps penetrate the skin and is essential for its binding activity.
Catalog NO: CT-AN2728
Synonym: Crisaborole
CAS NO: 906673-24-3
Mol. Formula: C14H10BNO3
MW: 251.08
** A snow-white crystalline powder (see attached picture), >99.5% Purity + impeccable 1H-NMR + spot-on Quantitative Elemental Analysis. Bulk Stock! Same day shipping from Indianapolis USA.