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Home > Hydrolase Inhibitors/Modulators > PDE4 ( phosphodiesterase type 4) > AN2728 (Crisaborole)

AN2728 (Crisaborole)

AN2728 (Crisaborole) is a non-steroidal, topically administered, boron-containing, anti-inflammatory compound that inhibits Phosphodiesterase 4 (PDE4), mainly acting on Phosphodiesterase 4B (PDE4), activity and thereby suppresses the release of tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines, proteins believed to be involved in the immune response and inflammation. The boron atom helps penetrate the skin and is essential for its binding activity.

Catalog NO:	CT-AN2728
Synonym:	Crisaborole
CAS NO:	906673-24-3
Mol. Formula:	C₁₄H₁₀BNO₃
MW:	251.08

** A snow-white crystalline powder (see attached picture), >99.5% Purity + impeccable 1H-NMR + spot-on Quantitative Elemental Analysis. Bulk Stock! Same day shipping from Indianapolis USA.

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NO	Size	Price	In Stock	Quantity
1	10 mg	$100.00	YES
2	50 mg	$180.00	YES
3	100 mg	$280.00	YES
4	200 mg	$450.00	YES

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Solubility : Soluble in DMSO, alcohols and acetone

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% by HPLC

Original QC Data : HPLC, ¹HNMR and Quantitative Elemental Analysis Report

Please Pick Batch NO:

AN2728 (Crisaborole), Lot 02, Certificate of Analysis.pdf
AN2728, Lot 02, Visual Appearance.pdf

1. Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2010 Jan-Feb; 32(1):47-86.

2. Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2009 Nov; 31(9):597-633.

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