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Home > IDH (Isocitrate Dehydrogenase) Inhibitors > Mutant-IDH1 Inhibitor > AG-120 (Ivosidenib)

AG-120 (Ivosidenib)

AG-120 (Ivosidenib) is a first-in-class, orally bioavailable, selective and potent inhibitor of mutant isocitrate dehydrogenase-1 (IDH1). Optically (enantiomerically and diastereomerically) Pure AG-120 specifically inhibits a mutated form of IDH1 in the cytoplasm, blocking the formation of oncometabolite, 2-hydroxyglutarate (2HG), a substance believed to fuel cancer growth. AG-120 is currently in clinical evaluation.

Catalog NO:	CT-AG120
Synonym:	Ivosidenib, AG120
CAS NO:	1448347-49-6
Mol. Formula:	C28H22ClF3N6O3
MW:	583.0 (or, refer to the Certificate of Analysis, batch-specific)

** in vivo Quality Material. 99.9% by achiral and chiral HPLCs (Attached). A white recrystallized powder. Anhydrous, validated by a spot-on Elemental Analysis. Bulk stock (Discounted price for 1G, 2G, …,). Same day shipping.

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NO	Size	Price	In Stock	Quantity
1	10 mg	$100.00	YES
2	50 mg	$250.00	YES
3	100 mg	$390.00	YES
4	200 mg	$650.00	YES

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Solubility : Refer to Certificate

Storage : Refer to Certificate

Purity : >99.8% chemically pure (achiral HPLC), 100% Optically Pure (chiral HPLC)

Original QC Data : HPLC-MS, Chiral HPLC, 1H-NMR and Quantitative Elemental Analysis

Please Pick Batch NO:

AG-120 (Ivosidenib), Lot 02, Certificate of Analysis.pdf

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