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AG-120 (Ivosidenib)
AG-120 (Ivosidenib) is a first-in-class, orally bioavailable, selective and potent inhibitor of mutant isocitrate dehydrogenase-1 (IDH1). Optically (enantiomerically and diastereomerically) Pure AG-120 specifically inhibits a mutated form of IDH1 in the cytoplasm, blocking the formation of oncometabolite, 2-hydroxyglutarate (2HG), a substance believed to fuel cancer growth. AG-120 is currently in clinical evaluation.
Catalog NO: CT-AG120
Synonym: Ivosidenib, AG120
CAS NO: 1448347-49-6
Mol. Formula: C28H22ClF3N6O3
MW: 583.0 (or, refer to the Certificate of Analysis, batch-specific)
** in vivo Grade Material. 99.9-100% by achiral and chiral HPLCs. A white crystalline solid, single isomer (out of possible four). Clean and impeccable (see attached QC docs). Bulk stock!. Same day shipping.