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ACBI1 is a potent and cooperative PROTAC (proteolysis-targeting chimera) degrader of the BAF chromatin remodeling ATPase subunits SMARCA2 and SMARCA4 as well as the facultative BAF complex subunit PBRM1. It harnesses the von-Hippel-Landau (VHL) E3 ligase to recruit its targets via their bromodomains and can be used for in vitro as well as in vivo studies (Ref 1).
Catalog NO: CT-ACBI1
CAS NO: 2375564-55-7
Mol. Formula: C49H58FN9O7S
MW: 936.1
** in vivo Quality Material. >99% by achiral and chiral HPLCs (attached), with a spot-on quantitative elemental analysis. Bulk Stock!! Same day shipping.