ABT-263 (Novitoclax) - Chemietek

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Home > Bcl-2 Protein Inhibitors/Degraders > Bcl-2 Family Protein Inhibitors > ABT-263 (Novitoclax)

ABT-263 (Novitoclax)

ABT-263 (Navitoclax) is a potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, binding potently to both BCL-2 and BCL-XL with Ki values of <1 nM.

Catalog NO:	CT-A263
Synonym:	Navitoclax
CAS NO:	923564-51-6
Mol. Formula:	C₄₇H₅₅ClF₃N₅O₆S₃
MW:	974.6

** in vivo Quality Material. >99% by Achiral and Chiral HPLCs. Optically Pure Source (Beware of partially Racemized ABT-263 (w/ >10% wrong Isomer*) on market). Anhydrous, validated by a spot-on Elemental Analysis. Prompt.

Pricing and OrderingTechnical Data

QC & Certificates

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NO	Size	Price	In Stock	Quantity
1	10 mg	$75.00	YES
2	50 mg	$150.00	YES
3	100 mg	$250.00	YES
4	200 mg	$390.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99% by Achiral and Chiral HPLCs

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis**

Please Pick Batch NO:

ABT-263, Lot 06, Certificate of Analysis.pdf
ABT-263, Lot 06, Visual Appearance.pdf

1. Tse C et al., ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor. Cancer Res. 2008 May 1;68(9):3421-8.

* For vendors who fail to report Chiral HPLC analysis (Apparently try to hide something).

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