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Home > Kinase Inhibitors > CDK (Cyclin-dependent Kinase) > THZ-531

THZ-531

THZ-531 (THZ531) is a first-in-class inhibitor of Cyclin-Dependent Kinase 12 (CDK12) and 13 (CDK13) with IC50s of 158 and 69 nM, respectively (ref 1).

Catalog NO:	CT-THZ531
Synonym:
CAS NO:	1702809-17-3
Mol. Formula:	C30H32ClN7O2• HCl
MW:	594.5

** in vivo QUALITY Material. 99.5-100% pure by Achiral and Chiral HPLCs (Attached). Monohydrochloride, validated by a spot-on Quantitative Elemental Analysis. Bulk stock! Same day shipping.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	5 mg	$120.00	YES
2	10 mg	$160.00	YES
3	50 mg	$480.00	YES
4	100 mg	$850.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99.5% pure by achiral and chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

THZ531, Lot 01, Certificate of Analysis.pdf
THZ-531, Lot 01, Visual Appearance.pdf

1. Zhang T, et al. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol. 2016 Oct;12(10):876-84

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