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Home > Cell Cycle Modulators > KRAS-SOS1 Inhibitors > MRTX0902

MRTX0902

MRTX0902 is a potent, selective, brain-penetrant, and orally bioavailable inhibitor of the SOS1: KRAS complex, with SOS1 Binding K _i = 1.9 nM, and Cellullar IC ₅₀ = 29 nM (Ref. 1).

Catalog NO:	CT-MRTX0902
Synonym:	MRTX-0902
CAS NO:	2654743-22-1
Mol. Formula:	C22H24N6O·0.5H2O
MW:	397.5

** in vivo Quality Material. >99% by achiral and chiral HPLCs (see attached). Hemihydrate, validated with a spot-on Quantitative Elemental Analysis. Clean and impeccable. Bulk Stock!! Prompt

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	5 mg	$100.00	YES
2	10 mg	$150.00	YES
3	50 mg	$450.00	YES
4	100 mg	$650.00	YES
5	200 mg	$1,000.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99% by Achiral and Chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

MRTX0902, Lot 01, Certificate of Analysis.pdf

1. J. M. Ketcham, et al, Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1: KRAS Protein–Protein Interaction, J. Med. Chem. 2022, 65, 14, 9678–

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