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Home > Kinase Inhibitors > RAF (Rapidly Accelerated Fibrosarcoma) > LXH254 (Naporafenib)

LXH254 (Naporafenib)

LXH254 (Naporafenib) is a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF. It inhibits dimerized BRAF and CRAF, as well as monomeric BRAF, currently being evaluated for the Treatment of MAPK-Driven Tumors.

Catalog NO:	CT-LXH254
Synonym:	Naporafenib
CAS NO:	1800398-38-2
Mol. Formula:	C25H25F3N4O4
MW:	502.5

** in vivo Quality Material. >99% by HPLC. Anhydrous, validated by a spot-on Elemental Analysis. Bulk stock. Same Day Shipping.

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NO	Size	Price	In Stock	Quantity
1	5 mg	$100.00	YES
2	10 mg	$150.00	YES
3	50 mg	$450.00	YES
4	100 mg	$750.00	YES

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Solubility : refer to Certificate of Analysis

Storage : refer to Certificate of Analysis

Purity : >99% by HPLC

Original QC Data : HPLC, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

LXH254 (Naporafenib) Lot 01, Certificate of Analysis.pdf
LXH254 (Naporafenib), Lot 01, Visual Appearance.pdf

1. Kelli-Ann Monaco, et al, LXH254, a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF for the Treatment of MAPK-Driven Tumors, CLINICAL CANCER RESEARCH, DOI: 10.1158/1078-0432.CCR-20-2563 Published April 2021

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