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Home > Kinase Inhibitors > Akt/(PKB (Protein Kinase B) > GDC-0068

GDC-0068

GDC-0068 (Ipatasertib) is a potent, APT-competitive and orally available small molecule pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively, and with selectivity over more than other 200 screened kinases. It displays robust antitumor activity with activation of PI3K-Akt-mTOR pathway, and is currently in clinical evaluations.

Catalog NO:	CT-G0068
Synonym:	Ipatasertib, RG7440
CAS NO:	1001264-89-6
Mol. Formula:	C₂₄H₃₂ClN₅O₂∙
MW:	458.0 (or refer to the Certificate of Analysis, Batch-specific)

** in vivo Quality Material. >99% Purity by Achiral and Chiral HPLCs, free base (salt-free), validated by a spot-on Quantitative Elemental Analysis. Bulk, prompt.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	10 mg	$120.00	YES
2	50 mg	$300.00	YES
3	100 mg	$480.00	YES
4	200 mg	$840.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : 99% chem and stereomeric purity (HPLC and Chiral HPLC)

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis

Please Pick Batch NO:

GDC-0068 (Ipatasertib), Lot 02, Certificate of Analysis.pdf
GDC-0068 (Ipatasertib), Lot 02, Visual Appearance.pdf

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